HPV: An update on Pathobiology and Diagnosis

Pranay Tanwar, Ritesh Kumar


The Human Papilloma Virus (HPV) associated cancers is being represented as a special subgroup of cancers nowadays because of its severity and increased mortality rates. HPV is known to integrate with the host tissue and causes carcinogenesis in a phased manner. With vaccination, the incidence of HPV associated cancers can be decreased. With the use of different HPV based screening tests, they can be detected early. Overall, HPV associated cancers have a good prognosis as compared to the non-HPV subtype and there is a growing thought on treatment de-escalation in these tumors to decrease long term treatment related toxicities.

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